PWP1 promotes nutrient-responsive expression of 5S ribosomal RNA
PWP1 is a chromatin binding protein with an important role in animal growth control downstream of mTOR-mediated nutrient sensing. PWP1 has been shown to control tissue growth by promoting the transcription of 5.8S, 18S and 28S ribosomal RNAs (rRNAs) by RNA polymerase I (Pol I). Concomitantly with Po...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2018-11-01
|
Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/7/11/bio037911 |