Proinflammatory T cell polarization is already present in patients with early knee osteoarthritis

Proinflammatory T cell polarization is already present in patients with early knee osteoarthritis

Abstract Background Investigating the pathophysiological mechanisms of early osteoarthritis (OA) is of utmost interest since this stage holds the strongest promise for therapeutic interventions. The aims of this study were to analyze if synovial inflammation is already present in early OA and to cha...

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Bibliographic Details
Main Authors: Nils Rosshirt, Richard Trauth, Hadrian Platzer, Elena Tripel, Timo A. Nees, Hanns-Martin Lorenz, Theresa Tretter, Babak Moradi
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Arthritis Research & Therapy
Subjects:
Early OA
T cell polarization
T helper cells
Inflammatory T cells
Synovial membrane
Synovial fluid
Online Access:https://doi.org/10.1186/s13075-020-02410-w

Internet

https://doi.org/10.1186/s13075-020-02410-w

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