Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology

Reactive oxygen species (ROS) are byproducts of aerobic respiration and signaling molecules that control various cellular functions. Nrf2 governs the gene expression of endogenous antioxidant synthesis and ROS-eliminating enzymes in response to various electrophilic compounds that inactivate the neg...

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Bibliographic Details
Main Authors: Shuya Kasai, Sunao Shimizu, Yota Tatara, Junsei Mimura, Ken Itoh
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/2/320