The Action Mode of Lysophosphatidylcholine in Human Monocytes

To elucidate the action and signal transduction of lysophosphatidylcholine (LPC), we challenged a set of LPC on U937 human monocytes and found that LPC mobilized Ca2+. The Ca2+ response was not blocked by pertussis toxin, an inhibitor of Gi/o proteins, or by U73122, a phospholipase C inhibitor. Furt...

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Bibliographic Details
Main Authors: Mi-Ran Yun, Fumikazu Okajima, Dong-Soon Im
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319325356