Betulinic Acid Exerts Cytoprotective Activity on Zika Virus-Infected Neural Progenitor Cells

Betulinic Acid Exerts Cytoprotective Activity on Zika Virus-Infected Neural Progenitor Cells

Zika virus (ZIKV), a member of the Flaviviridae family, was brought into the spotlight due to its widespread and increased pathogenicity, including Guillain-Barré syndrome and microcephaly. Neural progenitor cells (NPCs), which are multipotent cells capable of differentiating into the major neural p...

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Bibliographic Details
Main Authors: Bruno R. R. Cavalcante, Luciana S. Aragão-França, Gabriela L. A. Sampaio, Carolina K. V. Nonaka, Moisés S. Oliveira, Gúbio S. Campos, Silvia I. Sardi, Beatriz R. S. Dias, Juliana P. B. Menezes, Vinícius P. C. Rocha, Erik A. Rossi, Bruno D. Paredes, Gabriele L. S. Martins, Kyan J. Allahdadi, Laisla R. Peixoto, José M. Barbosa-Filho, Bruno S. F. Souza, Milena B. P. Soares
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Zika virus
neural progenitor cells
betulinic acid
apoptosis
neuroprotection
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.558324/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2020.558324/full

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