Induction of Apoptosis in TNF-Treated L929 Cells in the Presence of Necrostatin-1

It has been shown that necroptosis—caspase-independent programmed necrotic cell death—can be induced by treatment with tumor necrosis factor (TNF) in the L929 murine fibrosarcoma cell line, even in the absence of a caspase inhibitor. Although it was reported that necrostatin-1—a specific inhibitor o...

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Bibliographic Details
Main Author: Hirofumi Sawai
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:International Journal of Molecular Sciences
Subjects:
TNF
Online Access:http://www.mdpi.com/1422-0067/17/10/1678