The CpG Dinucleotide Adjacent to a κB Site Affects NF-κB Function through Its Methylation

The CpG Dinucleotide Adjacent to a κB Site Affects NF-κB Function through Its Methylation

NF-κB is an important transcription factor that plays critical roles in cell survival, proliferation, inflammation, and cancers. Although the majority of experimentally identified functional NF-κB binding sites (κB sites) match the consensus sequence, there are plenty of non-functional NF-κB consens...

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Bibliographic Details
Main Authors: Tao Wang, Jinge Li, Ke Ding, Li Zhang, Qiuru Che, Xiuming Sun, Yumeng Dai, Wei Sun, Meiying Bao, Xiaochun Wang, Liquan Yang, Zhiwei Li
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:International Journal of Molecular Sciences
Subjects:
NF-κB
consensus sequence
CpG islands
methylation
Online Access:http://www.mdpi.com/1422-0067/18/3/528

Internet

http://www.mdpi.com/1422-0067/18/3/528

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