Drug-evoked plasticity: do addictive drugs reopen a critical period of postnatal synaptic development?

As in other parts of the central nervous system of the mouse, glutamatergic synapses onto dopamine (DA) neurons in the ventral tegmental area (VTA) mature postnatally. At birth many AMPARs lack GluA2R subunit and most NMDARs contain the GluN2B subunit. Within two weeks these receptors are replaced w...

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Bibliographic Details
Main Authors: Camilla eBellone, Christian eLuscher
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
VTA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00075/full