Calibration-Less DNA Concentration Measurements Using EOF Volumetric Flow and Single Molecule Counting
Nanopore sensing is a promising tool well suited to capture and detect DNA and other single molecules. DNA is a negatively charged biomolecule that can be captured and translocated through a constricted nanopore aperture under an applied electric field. Precise assessment of DNA concentration is of...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-08-01
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Series: | Frontiers in Nanotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnano.2021.689584/full |