Calibration-Less DNA Concentration Measurements Using EOF Volumetric Flow and Single Molecule Counting

Nanopore sensing is a promising tool well suited to capture and detect DNA and other single molecules. DNA is a negatively charged biomolecule that can be captured and translocated through a constricted nanopore aperture under an applied electric field. Precise assessment of DNA concentration is of...

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Bibliographic Details
Main Authors: Nasim Farajpour, Lauren S. Lastra, Vinay Sharma, Kevin J. Freedman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Nanotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnano.2021.689584/full