Assessment of the Alveolar Capillary Network in the Postnatal Mouse Lung in 3D Using Serial Block-Face Scanning Electron Microscopy

Assessment of the Alveolar Capillary Network in the Postnatal Mouse Lung in 3D Using Serial Block-Face Scanning Electron Microscopy

The alveolar capillary network (ACN) has a large surface area that provides the basis for an optimized gas exchange in the lung. It needs to adapt to morphological changes during early lung development and alveolarization. Structural alterations of the pulmonary vasculature can lead to pathological...

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Bibliographic Details
Main Authors: Tobias Buchacker, Christian Mühlfeld, Christoph Wrede, Willi L. Wagner, Richard Beare, Matt McCormick, Roman Grothausmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Physiology
Subjects:
serial block-face scanning electron microscopy
lung
capillary network
3D reconstruction
segmentation
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01357/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01357/full

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