Polyamine Metabolism and Gene Methylation in Conjunction with One-Carbon Metabolism
Recent investigations have revealed that changes in DNA methylation status play an important role in aging-associated pathologies and lifespan. The methylation of DNA is regulated by DNA methyltransferases (DNMT1, DNMT3a, and DNMT3b) in the presence of S-adenosylmethionine (SAM), which serves as a m...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-10-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | http://www.mdpi.com/1422-0067/19/10/3106 |