High-Resolution Optical Molecular Imaging of Changes in Choline Metabolism in Oral Neoplasia

This study was aimed at developing an optical molecular imaging approach to measure differences in uptake and intracellular retention of choline in clinically isolated tissue biopsies from head and neck cancer patients. An optically detectable analogue of choline (propargyl choline) was synthesized...

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Bibliographic Details
Main Authors: Zhen Luo, Melissa Loja, D. Greg Farwell, Quang C. Luu, Paul J. Donald, Deborah Amott, Regina Gandour-Edwards, Nitin Nitin
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S193652331380040X