CONSTRICTOR: constraint modification provides insight into design of biochemical networks.

Advances in computational methods that allow for exploration of the combinatorial mutation space are needed to realize the potential of synthetic biology based strain engineering efforts. Here, we present Constrictor, a computational framework that uses flux balance analysis (FBA) to analyze inhibit...

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Bibliographic Details
Main Authors: Keesha E Erickson, Ryan T Gill, Anushree Chatterjee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4244162?pdf=render