Impact of Different Positive End-Expiratory Pressures on Lung Mechanics in the Setting of Moderately Elevated Intra-Abdominal Pressure and Acute Lung Injury in a Porcine Model

Impact of Different Positive End-Expiratory Pressures on Lung Mechanics in the Setting of Moderately Elevated Intra-Abdominal Pressure and Acute Lung Injury in a Porcine Model

The effects of a moderately elevated intra-abdominal pressure (IAP) on lung mechanics in acute respiratory distress syndrome (ARDS) have still not been fully analyzed. Moreover, the optimal positive end-expiratory pressure (PEEP) in elevated IAP and ARDS is unclear. In this paper, 18 pigs under gene...

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Bibliographic Details
Main Authors: Mascha O. Fiedler, Emilis Simeliunas, B. Luise Deutsch, Dovile Diktanaite, Alexander Harms, Maik Brune, Maximilian Dietrich, Florian Uhle, Markus A. Weigand, Armin Kalenka
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Journal of Clinical Medicine
Subjects:
ALI
ARDS
intraabdominal pressure
PEEP
end-expiratory lung volume
transpulmonary pressure
Online Access:https://www.mdpi.com/2077-0383/10/2/306

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https://www.mdpi.com/2077-0383/10/2/306

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