Determination of maximum tolerated dose and toxicity of Inauhzin in mice

Reactivating the tumor suppressor p53 offers an attractive strategy for developing cancer therapy. We recently identified Inauhzin (INZ) as a novel non-genotoxic p53-activating compound. To develop INZ into a clinically applicable anticancer drug, we have initiated preclinical toxicity studies. Here...

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Bibliographic Details
Main Authors: Qi Zhang, Shelya X. Zeng, Hua Lu
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221475001500030X