Determination of maximum tolerated dose and toxicity of Inauhzin in mice
Reactivating the tumor suppressor p53 offers an attractive strategy for developing cancer therapy. We recently identified Inauhzin (INZ) as a novel non-genotoxic p53-activating compound. To develop INZ into a clinically applicable anticancer drug, we have initiated preclinical toxicity studies. Here...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-01-01
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Series: | Toxicology Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221475001500030X |