A multiscale model of early cell lineage specification including cell division

Author summary The early development of the mammalian embryo involves cell divisions and highly regulated lineage specification events. Cell fates are determined by gene regulatory networks exhibiting multiple steady states. The question arises as to how these networks interact with extracellular si...

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Bibliographic Details
Main Authors: Alen Tosenberger, Didier Gonze, Sylvain Bessonnard, Michel Cohen-Tannoudji, Claire Chazaud, Geneviève Dupont
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-017-0017-0