Specific Inhibition of HIF Activity: Can Peptides Lead the Way?

Reduced oxygen availability (hypoxia) is a characteristic of many disorders including cancer. Central components of the systemic and cellular response to hypoxia are the Hypoxia Inducible Factors (HIFs), a small family of heterodimeric transcription factors that directly or indirectly regulate the e...

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Bibliographic Details
Main Authors: Ilias Mylonis, Georgia Chachami, George Simos
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
HIF
Online Access:https://www.mdpi.com/2072-6694/13/3/410