Genome-wide pQTL analysis of protein expression regulatory networks in the human liver

Abstract Background Previous expression quantitative trait loci (eQTL) studies have identified thousands of genetic variants to be associated with gene expression at the mRNA level in the human liver. However, protein expression often correlates poorly with mRNA levels. Thus, protein quantitative tr...

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Bibliographic Details
Main Authors: Bing He, Jian Shi, Xinwen Wang, Hui Jiang, Hao-Jie Zhu
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12915-020-00830-3