2-Hydroxy-4-Methylbenzoic Anhydride Inhibits Neuroinflammation in Cellular and Experimental Animal Models of Parkinson’s Disease

2-Hydroxy-4-Methylbenzoic Anhydride Inhibits Neuroinflammation in Cellular and Experimental Animal Models of Parkinson’s Disease

Microglia-mediated neuroinflammation is one of the key mechanisms involved in acute brain injury and chronic neurodegeneration. This study investigated the inhibitory effects of 2-hydroxy-4-methylbenzoic anhydride (HMA), a novel synthetic derivative of HTB (3-hydroxy-4-trifluoromethylbenzoic acid) o...

Full description

Bibliographic Details
Main Authors: Soo-Yeol Song, In-Su Kim, Sushruta Koppula, Ju-Young Park, Byung-Wook Kim, Sung-Hwa Yoon, Dong-Kug Choi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
microglia
neuroinflammation
nuclear factor kappa beta
interleukin
nitric oxide
Parkinson’s disease
Online Access:https://www.mdpi.com/1422-0067/21/21/8195

Internet

https://www.mdpi.com/1422-0067/21/21/8195

Similar Items