Foxc1 establishes enhancer accessibility for craniofacial cartilage differentiation
The specification of cartilage requires Sox9, a transcription factor with broad roles for organogenesis outside the skeletal system. How Sox9 and other factors gain access to cartilage-specific cis-regulatory regions during skeletal development was unknown. By analyzing chromatin accessibility durin...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-01-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/63595 |