Foxc1 establishes enhancer accessibility for craniofacial cartilage differentiation

The specification of cartilage requires Sox9, a transcription factor with broad roles for organogenesis outside the skeletal system. How Sox9 and other factors gain access to cartilage-specific cis-regulatory regions during skeletal development was unknown. By analyzing chromatin accessibility durin...

Full description

Bibliographic Details
Main Authors: Pengfei Xu, Haoze V Yu, Kuo-Chang Tseng, Mackenzie Flath, Peter Fabian, Neil Segil, J Gage Crump
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/63595