ER-Negative Breast Cancer Is Highly Responsive to Cholesterol Metabolite Signalling

ER-Negative Breast Cancer Is Highly Responsive to Cholesterol Metabolite Signalling

Interventions that alter cholesterol have differential impacts on hormone receptor positive- and negative-breast cancer risk and prognosis. This implies differential regulation or response to cholesterol within different breast cancer subtypes. We evaluated differences in side-chain hydroxycholester...

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Bibliographic Details
Main Authors: Samantha A Hutchinson, Priscilia Lianto, Hanne Roberg-Larsen, Sebastiano Battaglia, Thomas A Hughes, James L Thorne
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Nutrients
Subjects:
cholesterol
hydroxycholesterol
breast cancer
lxr
oestrogen receptor status
corepressors
Online Access:https://www.mdpi.com/2072-6643/11/11/2618

Internet

https://www.mdpi.com/2072-6643/11/11/2618

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