Total Flavones of Abelmoschus manihot Remodels Gut Microbiota and Inhibits Microinflammation in Chronic Renal Failure Progression by Targeting Autophagy-Mediated Macrophage Polarization

Total Flavones of Abelmoschus manihot Remodels Gut Microbiota and Inhibits Microinflammation in Chronic Renal Failure Progression by Targeting Autophagy-Mediated Macrophage Polarization

BackgroundRecently, progression of chronic renal failure (CRF) has been closely associated with gut microbiota dysbiosis and intestinal metabolite-derived microinflammation. In China, total flavones of Abelmoschus manihot (TFA), a component of Abelmoschus manihot, has been widely used to delay CRF p...

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Bibliographic Details
Main Authors: Yue Tu, Qi-Jun Fang, Wei Sun, Bu-Hui Liu, Ying-Lu Liu, Wei Wu, Hong-Yun Yee, Can-Can Yuan, Mei-Zi Wang, Zi-Yue Wan, Ren-Mao Tang, Yi-Gang Wan, Hai-Tao Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
chronic renal failure
total flavones of Abelmoschus manihot
gut microbiota
microinflammation
autophagy
macrophage polarization
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.566611/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.566611/full

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