Force and Calcium Transients Analysis in Human Engineered Heart Tissues Reveals Positive Force-Frequency Relation at Physiological Frequency

Summary: Force measurements in ex vivo and engineered heart tissues are well established. Analysis of calcium transients (CaT) is complementary to force, and the combined analysis is meaningful to the study of cardiomyocyte biology and disease. This article describes a model of human induced pluripo...

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Bibliographic Details
Main Authors: Umber Saleem, Ingra Mannhardt, Ingke Braren, Chris Denning, Thomas Eschenhagen, Arne Hansen
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119304503