Immunogenicity and protective efficacy against Treponema pallidum in New Zealand rabbits immunized with plasmid DNA encoding flagellin

Abstract Plasmid DNA encoding flagellin FlaB3 was used as a vaccination candidate for the evaluation of immunogenicity and protection against Treponema pallidum subsp. pallidum dissemination. First, intramuscular injection of the flagellin encoded by the plasmid DNA into New Zealand rabbits elicited...

Full description

Bibliographic Details
Main Authors: Kang Zheng, Man Xu, Yongjian Xiao, Haodang Luo, Yafeng Xie, Jian Yu, Manyi Tan, Yumeng Li, Feijun Zhao, Tiebing Zeng, Yimou Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:Emerging Microbes and Infections
Online Access:http://link.springer.com/article/10.1038/s41426-018-0176-0