Novel Molecular Mechanism of Aspirin and Celecoxib Targeting Mammalian Neuraminidase-1 Impedes Epidermal Growth Factor Receptor Signaling Axis and Induces Apoptosis in Pancreatic Cancer Cells

Novel Molecular Mechanism of Aspirin and Celecoxib Targeting Mammalian Neuraminidase-1 Impedes Epidermal Growth Factor Receptor Signaling Axis and Induces Apoptosis in Pancreatic Cancer Cells

Bessi Qorri,1 William Harless,2 Myron R Szewczuk1 1Department of Biomedical and Molecular Sciences, Queen’s University, Kingston, ON K7L 3N6, Canada; 2ENCYT Technologies Inc., Membertou, Nova Scotia, CanadaCorrespondence: Myron R SzewczukDepartment of Biomedical and Molecular Sciences, Que...

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Bibliographic Details
Main Authors: Qorri B, Harless W, Szewczuk MR
Format: Article
Language:English
Published: Dove Medical Press 2020-10-01
Series:Drug Design, Development and Therapy
Subjects:
neuraminidase-1
inflammation
cancer
multistage tumorigenesis
tumor microenvironment
Online Access:https://www.dovepress.com/novel-molecular-mechanism-of-aspirin-and-celecoxib-targeting-mammalian-peer-reviewed-article-DDDT

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https://www.dovepress.com/novel-molecular-mechanism-of-aspirin-and-celecoxib-targeting-mammalian-peer-reviewed-article-DDDT

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