Connexin 43 Channels in Osteocytes Regulate Bone Responses to Mechanical Unloading

Connexin 43 Channels in Osteocytes Regulate Bone Responses to Mechanical Unloading

Connexin (Cx) 43 forms gap junctions and hemichannels that mediate communication between osteocytes and adjacent cells or the extracellular environment in bone, respectively. To investigate the role of each channel type in response to mechanical unloading, two transgenic mouse models overexpressing...

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Bibliographic Details
Main Authors: Dezhi Zhao, Ruofei Liu, Guobin Li, Meng Chen, Peng Shang, Hui Yang, Jean X. Jiang, Huiyun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Physiology
Subjects:
Cx43
gap junction
hemichannel
hindlimb unloading
osteocyte
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00299/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00299/full

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