Combination of white matter hyperintensities and Aβ burden is related to cognitive composites domain scores in subjective cognitive decline: the FACEHBI cohort

Combination of white matter hyperintensities and Aβ burden is related to cognitive composites domain scores in subjective cognitive decline: the FACEHBI cohort

Abstract Background To explore whether the combination of white matter hyperintensities (WMHs) and amyloid-beta (Aβ) deposition is associated with worse cognitive performance on cognitive composites (CCs) domain scores in individuals with subjective cognitive decline (SCD). Methods Two hundred parti...

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Bibliographic Details
Main Authors: G. Ortega, A. Espinosa, M. Alegret, GC. Monté-Rubio, O. Sotolongo-Grau, A. Sanabria, JP. Tartari, O. Rodríguez-Gómez, M. Marquié, A. Vivas, M. Gómez-Chiari, E. Alarcón-Martín, A. Pérez-Cordón, N. Roberto, I. Hernández, M. Rosende-Roca, L. Vargas, A. Mauleón, C. Abdelnour, E. Esteban De Antonio, R. López-Cuevas, S. Alonso-Lana, S. Moreno-Grau, I. de Rojas, A. Orellana, L. Montrreal, L. Tárraga, A. Ruiz, M. Boada, S. Valero, FACEHBI group
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Alzheimer’s Research & Therapy
Subjects:
Amyloid-beta (Aß)
Apolipoprotein E
Cognitive composites domain scores
FBB-PET
Magnetic resonance imaging
Subjective cognitive decline
Online Access:https://doi.org/10.1186/s13195-021-00877-6

Internet

https://doi.org/10.1186/s13195-021-00877-6

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