AICAR Administration Attenuates Hemorrhagic Hyperglycemia and Lowers Oxygen Debt in Anesthetized Male Rabbits

AICAR Administration Attenuates Hemorrhagic Hyperglycemia and Lowers Oxygen Debt in Anesthetized Male Rabbits

Background: Many strategies have been utilized to treat traumatic shock via improved oxygen delivery (DO2), while fewer have been used to in an attempt to reduce oxygen demand (VO2). The cellular energy sensor 5′ adenosine monophosphate-activated protein kinase (AMPK) has the potential to modulate b...

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Bibliographic Details
Main Authors: Yi Huang, Paul H. Ratz, Amy S. Miner, Victoria A. Locke, Grace Chen, Yang Chen, Robert W. Barbee
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Physiology
Subjects:
AMPK
glucose transport
glucose oxidation
hemodynamics
ischemia
lactate
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00692/full

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http://journal.frontiersin.org/article/10.3389/fphys.2017.00692/full

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