Sensitive Detection of Single-Nucleotide Polymorphisms by Solid Nanopores Integrated With DNA Probed Nanoparticles

Single-nucleotide polymorphisms (SNPs) are the abundant forms of genetic variations, which are closely associated with serious genetic and inherited diseases, even cancers. Here, a novel SNP detection assay has been developed for single-nucleotide discrimination by nanopore sensing platform with DNA...

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Bibliographic Details
Main Authors: Ling Zhi Wu, Yuan Ye, Zhi Xuan Wang, Die Ma, Li Li, Guo Hao Xi, Bi Qing Bao, Li Xing Weng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.690747/full