DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system

DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system

Abstract Background CRISPR-Cas systems, which provide adaptive immunity against foreign nucleic acids in prokaryotes, can serve as useful molecular tools for multiple applications in genome engineering. Diverse CRISPR-Cas systems originating from distinct prokaryotes function through a common mechan...

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Bibliographic Details
Main Authors: Donata Tuminauskaite, Danguole Norkunaite, Marija Fiodorovaite, Sarunas Tumas, Inga Songailiene, Giedre Tamulaitiene, Tomas Sinkunas
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Biology
Subjects:
CRISPR-Cas immunity
CRISPR protection
type I-F
Cascade
Csy
R-loop
Online Access:http://link.springer.com/article/10.1186/s12915-020-00799-z

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http://link.springer.com/article/10.1186/s12915-020-00799-z

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