Efficient Cre/loxP Site-Specific Recombination in a HepG2 Human Liver Cell Line

Efficient Cre/loxP Site-Specific Recombination in a HepG2 Human Liver Cell Line

A worldwide shortage of donor livers is a limiting factor of the clinical application of hepatocyte transplantation (HTX). To resolve this issue, we focused on a reversible immortalization system that allows temporary expansion of primary hepatocyte populations by transfer of an oncogene that can be...

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Main Authors: Naoya Kobayashi M.D., Ph.D., Hirofumi Noguchi, Karen A. Westerman, Toshihisa Matsumura, Takamasa Watanabe, Toshinori Totsugawa, Toshiyoshi Fujiwara, Philippe Leboulch, Noriaki Tanaka
Format: Article
Language:English
Published: SAGE Publishing 2000-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368970000900525

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https://doi.org/10.1177/096368970000900525

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