Low plasma stem cell factor combined with high transforming growth factor-α identifies high-risk patients in pulmonary arterial hypertension
In pulmonary arterial hypertension (PAH), severe vasoconstriction and remodelling of small pulmonary arteries result in high mortality. Receptor tyrosine kinases and their ligands, such as transforming growth factor (TGF)-α, modulate proliferation in PAH. Although the receptor tyrosine kinase c-Kit...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2018-11-01
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| Series: | ERJ Open Research |
| Online Access: | http://openres.ersjournals.com/content/4/4/00035-2018.full |