The TCR Repertoire Reconstitution in Multiple Sclerosis: Comparing One-Shot and Continuous Immunosuppressive Therapies

The TCR Repertoire Reconstitution in Multiple Sclerosis: Comparing One-Shot and Continuous Immunosuppressive Therapies

Natalizumab (NTZ) and autologous hematopoietic stem cell transplantation (AHSCT) are two successful treatments for relapsing-remitting multiple sclerosis (RRMS), an autoimmune T-cell-driven disorder affecting the central nervous system that is characterized by relapses interspersed with periods of c...

Full description

Bibliographic Details
Main Authors: Roberta Amoriello, Victor Greiff, Alessandra Aldinucci, Elena Bonechi, Alberto Carnasciali, Benedetta Peruzzi, Anna Maria Repice, Alice Mariottini, Riccardo Saccardi, Benedetta Mazzanti, Luca Massacesi, Clara Ballerini
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
system immunology
T-cell subpopulations
T-cell repertoire diversity
multiple sclerosis
disease-modifying therapies
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00559/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00559/full

Similar Items