Targeting the insulin-like growth factor receptor pathway in lung cancer: problems and pitfalls

The insulin-like growth factor (IGF) pathway is a complex pathway involving interactions between membrane-bound receptors, ligands, binding proteins, downstream effectors, and other receptor tyrosine kinase signaling cascades. The IGF pathway has been identified as a potential therapeutic target in...

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Bibliographic Details
Main Authors: Mary Jo Fidler, David D. Shersher, Jeffrey A. Borgia, Philip Bonomi
Format: Article
Language:English
Published: SAGE Publishing 2012-03-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758834011427576