Resting State Functional Connectivity Is Decreased Globally Across the C9orf72 Mutation Spectrum

Resting State Functional Connectivity Is Decreased Globally Across the C9orf72 Mutation Spectrum

A repeat expansion mutation in the C9orf72 gene causes amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), or symptoms of both, and has been associated with gray and white matter changes in brain MRI scans. We used graph theory to examine the network properties of brain function at r...

Full description

Bibliographic Details
Main Authors: Rachel F. Smallwood Shoukry, Michael G. Clark, Mary Kay Floeter
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Neurology
Subjects:
C9orf72
amyotrophic lateral sclerosis
behavioral variant frontotemporal dementia
pre-symptomatic
resting state fMRI
graph theory
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.598474/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2020.598474/full

Similar Items