Hepatitis C Virus NS5A Protein Triggers Oxidative Stress by Inducing NADPH Oxidases 1 and 4 and Cytochrome P450 2E1

Replication of hepatitis C virus (HCV) is associated with the induction of oxidative stress, which is thought to play a major role in various liver pathologies associated with chronic hepatitis C. NS5A protein of the virus is one of the two key viral proteins that are known to trigger production of...

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Bibliographic Details
Main Authors: Olga A. Smirnova, Olga N. Ivanova, Birke Bartosch, Vladimir T. Valuev-Elliston, Furkat Mukhtarov, Sergey N. Kochetkov, Alexander V. Ivanov
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/8341937