Lack of Brain Serotonin Affects Feeding and Differentiation of Newborn Cells in the Adult Hypothalamus

Serotonin (5-HT) is a crucial signal in the neurogenic niche microenvironment. Dysregulation of the 5-HT system leads to mood disorders but also to changes in appetite and metabolic rate. Tryptophan hydroxylase 2-deficient (Tph2-/-) mice depleted of brain 5-HT display alterations in these parameters...

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Bibliographic Details
Main Authors: Marike van Lingen, Maria Sidorova, Natalia Alenina, Friederike Klempin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
NG2
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00065/full