Analgesic activity of some aroylhydrazone-based molecular hybrids with antiseizure activity: in vivo and in silico evaluations

Analgesic activity of some aroylhydrazone-based molecular hybrids with antiseizure activity: in vivo and in silico evaluations

We have recently identified several aroylhydrazone-based molecular hybrids with antiseizure activity. We aimed to investigate the analgesic activity of these molecules further. Male ICR mice were injected intraperitoneally with the tested substances or with the vehicle only (controls). We performed...

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Bibliographic Details
Main Authors: Stanislav Marchev, Pavlina Andreeva-Gateva, Roumiana Tzoneva, Slavina Surcheva, Alex Tzonev, Kalina Kamenova, Violina T. Angelova, Jana Tchekalarova, Mila Vlaskovska
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
aroylhydrazones
antiseizure
analgesic
cytokines
proteome
hmgcs2
Online Access:http://dx.doi.org/10.1080/13102818.2018.1555009

Internet

http://dx.doi.org/10.1080/13102818.2018.1555009

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