Ozone therapy could attenuate tubulointerstitial injury in adenine-induced CKD rats by mediating Nrf2 and NF-κB

Ozone therapy could attenuate tubulointerstitial injury in adenine-induced CKD rats by mediating Nrf2 and NF-κB

Objective(s): This study aims to determine the effects of ozone therapy on restoring impaired Nrf2 activation to ameliorate chronic tubulointerstitial injury in rats with adenine-induced CKD. Materials and Methods: Sprague–Dawley rats were fed with 0.75% adenine-containing diet to induce CKD and chr...

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Bibliographic Details
Main Authors: Gang Yu, Xiuheng Liu, Zhiyuan Chen, Hui Chen, Lei Wang, Zhishun Wang, Tao Qiu, Xiaodong Weng
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-10-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Adenine
Nuclear factor erythroid-2-related factor 2
Ozone therpy
Rat
Tubuleinterstitial injury
Online Access:http://ijbms.mums.ac.ir/article_7740_fc291e43d86871dc9b147fa15118bc44.pdf

Internet

http://ijbms.mums.ac.ir/article_7740_fc291e43d86871dc9b147fa15118bc44.pdf

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