Molecular Insights into an Antibiotic Enhancer Action of New Morpholine-Containing 5-Arylideneimidazolones in the Fight against MDR Bacteria

Molecular Insights into an Antibiotic Enhancer Action of New Morpholine-Containing 5-Arylideneimidazolones in the Fight against MDR Bacteria

In the search for an effective strategy to overcome antimicrobial resistance, a series of new morpholine-containing 5-arylideneimidazolones differing within either the amine moiety or at position five of imidazolones was explored as potential antibiotic adjuvants against Gram-positive and Gram-negat...

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Bibliographic Details
Main Authors: Aneta Kaczor, Karolina Witek, Sabina Podlewska, Veronique Sinou, Joanna Czekajewska, Ewa Żesławska, Agata Doroz-Płonka, Annamaria Lubelska, Gniewomir Latacz, Wojciech Nitek, Markus Bischoff, Sandrine Alibert, Jean-Marie Pagès, Claus Jacob, Elżbieta Karczewska, Jean-Michel Bolla, Jadwiga Handzlik
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
5-arylideneimidazolones
multidrug resistance
antibiotic adjuvant
<i>Staphylococcus</i> <i>aureus</i>
MRSA
<i>Klebsiella aerogenes</i>
Online Access:https://www.mdpi.com/1422-0067/22/4/2062

Internet

https://www.mdpi.com/1422-0067/22/4/2062

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