A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries

<p>Abstract</p> <p>Background</p> <p>The identification of novel drug targets by assessing gene functions is most conveniently achieved by high-throughput loss-of-function RNA interference screening. There is a growing need to employ primary cells in such screenings, si...

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Main Authors: Knappik Achim, Lingnau Andreas, Waldherr Dirk, Brundiers Ralf, Hagner Ursula, Weise Frank, Thomas Maria, Klotzbücher Andrea, Oehmig Angelika, Kubbutat Michael HG, Joos Thomas O, Volkmer Hansjürgen
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/441