Oral transmissibility of prion disease is enhanced by binding to soil particles.

Soil may serve as an environmental reservoir for prion infectivity and contribute to the horizontal transmission of prion diseases (transmissible spongiform encephalopathies [TSEs]) of sheep, deer, and elk. TSE infectivity can persist in soil for years, and we previously demonstrated that the diseas...

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Bibliographic Details
Main Authors: Christopher J Johnson, Joel A Pedersen, Rick J Chappell, Debbie McKenzie, Judd M Aiken
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0030093