Cognitive training at a young age attenuates deficits in the zQ175 mouse model of HD

Cognitive training at a young age attenuates deficits in the zQ175 mouse model of HD

Huntington’s Disease (HD) is a progressive neurodegenerative disorder that causes motor, cognitive, and psychiatric symptoms. In these experiments, we tested if operant training at an early age affected adult cognitive deficits in the zQ175 KI Het (zQ175) mouse model of HD. In Experiment 1 we traine...

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Bibliographic Details
Main Authors: Paul C.P. Curtin, Andrew M Farrar, Stephen eOakeshott, Jane eSutphen, Jason eBerger, Matthew eMazzella, Kimberly eCox, Dansha eHe, William eAlosio, Larry ePark, David eHowland, Daniela eBrunner
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Huntington's disease
brain training
environmental enrichment
Cognitive Load
zQ175
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00361/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00361/full

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