Downregulation of Heme Oxygenase 1 (HO-1) Activity in Hematopoietic Cells Enhances Their Engraftment after Transplantation

Heme oxygenase 1 (HO-1) is an inducible stress-response enzyme that not only catalyzes the degradation of heme (e.g., released from erythrocytes) but also has an important function in various physiological and pathophysiological states associated with cellular stress, such as ischemic/reperfusion in...

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Bibliographic Details
Main Authors: Mateusz Adamiak, Joseph B. Moore, John Zhao, Ahmed Abdelbaset-Ismail, Kamil Grubczak, Sylwia Rzeszotek, Marcin Wysoczynski, Mariusz Z. Ratajczak M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2016-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368915X688957