Perineurial Barrier Glia Physically Respond to Alcohol in an Akap200-Dependent Manner to Promote Tolerance
Summary: Ethanol is the most common drug of abuse. It exerts its behavioral effects by acting on widespread neural circuits; however, its impact on glial cells is less understood. We show that Drosophila perineurial glia are critical for ethanol tolerance, a simple form of behavioral plasticity. The...
Main Authors: | Sarah J. Parkhurst, Pratik Adhikari, Jovana S. Navarrete, Arièle Legendre, Miguel Manansala, Fred W. Wolf |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-02-01
|
Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718300810 |
Similar Items
-
Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination
by: Brian W Jones, et al.
Published: (2016-12-01) -
Molecular evolution of a-kinase anchoring protein (AKAP)-7: implications in comparative PKA compartmentalization
by: Johnson Keven R, et al.
Published: (2012-07-01) -
Compartmentalization Role of A-Kinase Anchoring Proteins (AKAPs) in Mediating Protein Kinase A (PKA) Signaling and Cardiomyocyte Hypertrophy
by: Abeer Rababa'h, et al.
Published: (2014-12-01) -
AKAP6 and phospholamban colocalize and interact in HEK‐293T cells and primary murine cardiomyocytes
by: Farigol Hakem Zadeh, et al.
Published: (2019-07-01) -
Disruption of AKAP-PKA Interaction Induces Hypercontractility With Concomitant Increase in Proliferation Markers in Human Airway Smooth Muscle
by: Hoeke A. Baarsma, et al.
Published: (2020-04-01)