Perineurial Barrier Glia Physically Respond to Alcohol in an Akap200-Dependent Manner to Promote Tolerance

Summary: Ethanol is the most common drug of abuse. It exerts its behavioral effects by acting on widespread neural circuits; however, its impact on glial cells is less understood. We show that Drosophila perineurial glia are critical for ethanol tolerance, a simple form of behavioral plasticity. The...

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Bibliographic Details
Main Authors: Sarah J. Parkhurst, Pratik Adhikari, Jovana S. Navarrete, Arièle Legendre, Miguel Manansala, Fred W. Wolf
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Cell Reports
Subjects:
PKA
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718300810