In vitro synergism of simvastatin and fluconazole against Candida species

Systemic fungal infections are responsible for high mortality rates. Several species of fungi may be involved, but Candida spp. is the most prevalent. Simvastatin is used to lower cholesterol and also exhibits antifungal action. The aim of this study was to evaluate the synergistic action of simvast...

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Bibliographic Details
Main Authors: Everardo Albuquerque Menezes, Antônio Alexandre de Vasconcelos Júnior, Carlla Lorena Façanha Silva, Fábio Ximenes Plutarco, Maria da Conceição dos Santos Oliveira Cunha, Francisco Afrânio Cunha
Format: Article
Language:English
Published: Universidade de São Paulo 2012-08-01
Series:Revista do Instituto de Medicina Tropical de São Paulo
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652012000400003&lng=en&tlng=en