HPV-16 E6/E7 DNA tattoo vaccination using genetically optimized vaccines elicit clinical and immunological responses in patients with usual vulvar intraepithelial neoplasia (uVIN): a phase I/II clinical trial

HPV-16 E6/E7 DNA tattoo vaccination using genetically optimized vaccines elicit clinical and immunological responses in patients with usual vulvar intraepithelial neoplasia (uVIN): a phase I/II clinical trial

Background Usual vulvar intraepithelial neoplasia (uVIN) is a premalignancy caused by persistent infection with high-risk types of human papillomavirus (HPV), mainly type 16. Even though different treatment modalities are available (eg, surgical excision, laser evaporation or topical application of...

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Bibliographic Details
Main Authors: Nienke E van Trommel, Gemma G Kenter, John Haanen, Tanja D de Gruijl, Sanne Samuels, Ekaterina S Jordanova, Ton Schumacher, Joost H van den Berg, Bastiaan Nuijen, Jos Beijnen, Marc van Beurden, Noor Alida Maria Bakker, Jossie Rotman, Henry J MAA Zijlmans, Maartje van Ruiten, Karin De Visser
Format: Article
Language:English
Published: BMJ Publishing Group 2021-08-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/8/e002547.full

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https://jitc.bmj.com/content/9/8/e002547.full

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