Gene Polymorphism of Toll-Like Receptors and Lung Function at Five to Seven Years of Age after Infant Bronchiolitis.

AIM:Toll-like receptors (TLR) play a crucial role in innate immunity, protecting the host from pathogens such as viruses. Genetic variations in TLRs have been associated with the severity of viral bronchiolitis in infancy and with the later occurrence of post-bronchiolitis asthma. The aim of the pre...

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Main Authors: Eero Lauhkonen, Petri Koponen, Juho Vuononvirta, Johanna Teräsjärvi, Kirsi Nuolivirta, Jyri O Toikka, Merja Helminen, Qiushui He, Matti Korppi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4704821?pdf=render