Loss of FADS2 function severely impairs the use of HeLa cells as an in vitro model for host response studies involving fatty acid effects.

Loss of FADS2 function severely impairs the use of HeLa cells as an in vitro model for host response studies involving fatty acid effects.

Established epithelial cell lines equipped with pattern recognition receptors such as the Toll-like receptor (TLR)-2 are common tools for immune response studies on invading pathogens, e.g. the obligate intracellular species of Chlamydia. Moreover, such models are widely used to elucidate fatty acid...

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Bibliographic Details
Main Authors: Anke Jaudszus, Christian Degen, Stephan W Barth, Martin Klempt, Wiebke Schlörmann, Alexander Roth, Carsten Rohrer, Helga Sauerwein, Konrad Sachse, Gerhard Jahreis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4280191?pdf=render

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http://europepmc.org/articles/PMC4280191?pdf=render

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